Lipid Peroxidation, Free Radical Scavenging Enzymes, and Glutathione Redox System in Blood of Rats Exposed to Propoxur

摘要: Pesticides may induce oxidative stress leading to generation of free radicals and alterations in antioxidants or oxygen radical (OFR), scavenging enzymes. Hence, the effect subchronic/chronic propoxur (2-isopropoxy phenyl N-methyl carbamate) on lipid peroxidation, OFR enzymes, glutathione redox system was evaluated blood samples obtained from rats. Malondialdehyde level (in serum) activities superoxide dismutase catalase red cells), peroxidase whole blood), reductase plasma), S-transferase were increased a dose-dependent manner following administration (10, 30, 90 mg/kg body weight/day) for 30 days. However, decrease observed level. These results indicate possible involvement propoxur-induced toxicity. Increased peroxidation coupled with altered levels enzymes are discussed context stress.