Development of MALDI MS peptide array for thrombin inhibitor screening.
作者： Ping Li , Andrew Gordon , Bin Li , Weiwei Tang , Jun Chen
DOI: 10.1016/J.TALANTA.2021.122129
关键词: Cleavage (embryo) 、 Mass spectrometry imaging 、 Discovery and development of direct thrombin inhibitors 、 Matrix (chemical analysis) 、 Peptide 、 Chromatography 、 Thrombin 、 Polymerization 、 Chemistry 、 Amphiphile
摘要: The development of in situ methods for the analysis and visualization of enzyme activity is of paramount importance in drug discovery, research, and development. In this work, the …
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