A prospective, randomized study of goal-oriented hemodynamic therapy in cardiac surgical patients.

摘要: Organ dysfunction and multiple organ failure are the main causes of prolonged hospital stay after cardiac surgery, which increases resource use health care costs. Increased levels oxygen delivery consumption associated with improved outcome in different groups postoperative patients. Cardiac surgical patients at risk inadequate perioperative caused by extracorporeal circulation limited cardiovascular reserves. The purpose our study was to test whether increasing immediately surgery would shorten intensive unit (ICU) stay. Four hundred three elective were enrolled randomly assigned either control or protocol group. Goals group maintain Svo 2 >70% lactate concentration <=2.0 mmol/L from admission ICU up 8 h thereafter. Hemodynamics, transport data, dysfunctions recorded. median hos-pital shorter (6 vs 7 days, P < 0.05), discharged faster than those (P 0.05). Discharge similar between = 0.8). Morbidity less frequent time discharge (1.1% 6.1%, 0.01). Increasing achieve normal values during immediate period can length Implications: Health economics has challenged clinicians reduce costs improve anesthesia a patient population age severity disease. Optimizing function adequate decrease morbidity