Einwegsysteme in zellkulturbasierten Herstellprozessen für Biopharmazeutika

摘要: Production of biopharmaceuticals from mammalian cells is classically performed using stainless-steel tanks and pipes for cell culture, purification fill finish. Recently, disposable systems have been used successfully along the entire process flow up to 2.000 l scale. It will be crucial characterize these further in particular ensure a profound understanding reliable transfer between fully facilities.