作者: Thomas D. Christensen, Jørn Atterma
DOI: 10.1080/140174301750164772
关键词: Medicine 、 Prospective cohort study 、 Blood coagulation test 、 Heart valve 、 Prosthesis 、 Surgery 、 Case-control study 、 Oral administration 、 Anticoagulant 、 Retrospective cohort study
摘要: Objective - Self-management of oral anticoagulant therapy (OAT) has shown good results on a short-term basis. We hypothesize that self-management OAT provides better quality treatment than conventional management also long-term The aim this study was to assess the in patients with mechanical heart valve prostheses 4-year perspective prospective, non-randomized study. Design Twenty-four valves and self-managed were followed for up 4 years. A matched, retrospectively selected group conventionally managed (control group) used as reference. Results -The median observation time 1175 days (range: 174-1428 days). within therapeutic INR target range mean 78.0% 36.1%-93.9%) compared 61.0% (range 37.4%-2.9%) control group. Conclusion is feasible safe concept pa...