Factors Related to Long-Term Survival in Patients Affected by Well-Differentiated Endocrine Tumors of the Pancreas

摘要: Aim. To identify factors related to survival in patients affected by well-differentiated PETs (benign, uncertain behavior, and carcinoma) who underwent R0 pancreatic resection. Methods. Retrospective study of 74 consecutive followed up from January 1980 December 2011. Prognostic were sex, age, type tumor, presence symptoms, surgical procedure, size lymph nodes status, WHO classification, TNM stage. Overall was evaluated using the Kaplan-Meier method. Cox regression analyses used associated with prognosis univariate multivariate analysis. Results. The mean follow-up all 106 ± 89 months. 5-10-year long-term 90.9% 79.1%, respectively. At analysis, patient age <55 years significantly a better compared ≥55 (307 15 months versus 192 25 months; P = 0.010). Multivariate analysis showed that female gender (P 0.006), without comorbidities 0.033), benign endocrine tumors 0.008 0.002 relation behavior carcinomas, resp.) survival. Conclusions. Patients strongly observed. classification is very useful prognostic tool for PETs.