Epidemiological Studies of Ozone Exposure Effects

作者: George D. Thurston , Kazuhiko Ito

DOI: 10.1016/B978-012352335-8/50097-1

关键词: Respiratory diseaseEnvironmental healthIntensive care medicineConfoundingEpidemiologyMedicineRespiratory systemAdverse effectOzone exposureAcute effectsPopulation

摘要: Publisher Summary Aggregate population time-series epidemiology studies examining the acute effects of ambient O 3 have yielded significant associations with a wide range adverse health outcomes, including lung function decrements, aggravation pre-existing respiratory disease, increases in daily hospital admissions, and premature mortality. Individual-level camp clearly indicate that number asthma exacerbations their also are associated concentration, which corroborates reported aggregate-level associations. In addition, less severe effects, such as increased restricted activity days, decreased function, diminished athletic performance, can occur even healthy individuals. This indicates exposures not limited to especially susceptible subpopulations, but adversely affect large percentage general population. The emergency room visit admission collectively that, when major confounders addressed, consistent seen between occurrences morbidity exposures. evidence is strong for admissions this association has been by numerous researchers at variety localities using appropriate statistical approaches. Although absolute size effect varies somewhat across approaches, these analyses suggest air pollution substantial portion all visits summer.

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