Coronary and myocardial angiography: angiographic assessment of both epicardial and myocardial perfusion.

摘要: Angiographic assessment of epicardial coronary artery blood flow has played a pivotal role in our understanding the “time-dependent open hypothesis” and evaluation reperfusion strategies over past 2 decades.1–8 It become increasingly apparent, however, that clinical outcomes are not only associated with angiographic artery, but also myocardium.9–13 To this end, goal therapies shifted to include downstream at level capillary bed, it might be more appropriate hypothesis now termed “the time dependent microvascular hypothesis.” The article is review methods used evaluate myocardial ischemia infarction discuss insights into pathophysiology acute syndromes provided by these indexes perfusion. For nearly decades now, Thrombolysis In Myocardial Infarction (TIMI) grade classification scheme been successfully assess syndromes1 (Table). valuable tool compare following reperfusion, association TFGs (including mortality) well documented.2–8 relationship between TFG mortality does satisfy what some consider 3 criteria required validate surrogate end point for mortality, as follows: (1) There an TIMI (2) agent such recombinant tissue plasminogen activator improves 22% another streptokinase, (3) 1.1% streptokinase. View table: Definitions TMPG Systems On basis observed GUSTO …