Cell cycle proliferation decisions: the impact of single cell analyses.

作者: Jacob P. Matson , Jeanette G. Cook

DOI: 10.1111/FEBS.13898

关键词: DNA replicationCellCell growthCell biologyIntracellularRestriction pointCell cycleSingle-cell analysisCell divisionBiology

摘要: … cells, and the expression intensity and number of expressing … increasing CDK activity, cells exit to G0. The probability of … to the next cell cycle, and consequently a short G1 phase. …

参考文章(105)
Cheng-Zhong Zhang, Alexander Spektor, Hauke Cornils, Joshua M. Francis, Emily K. Jackson, Shiwei Liu, Matthew Meyerson, David Pellman, Chromothripsis from DNA damage in micronuclei Nature. ,vol. 522, pp. 179- 184 ,(2015) , 10.1038/NATURE14493
S Dobrowolski, M Harter, D W Stacey, Cellular ras activity is required for passage through multiple points of the G0/G1 phase in BALB/c 3T3 cells. Molecular and Cellular Biology. ,vol. 14, pp. 5441- 5449 ,(1994) , 10.1128/MCB.14.8.5441
Jérémy Huard, Stephanie Mueller, Ernst D. Gilles, Ursula Klingmüller, Steffen Klamt, An integrative model links multiple inputs and signaling pathways to the onset of DNA synthesis in hepatocytes FEBS Journal. ,vol. 279, pp. 3290- 3313 ,(2012) , 10.1111/J.1742-4658.2012.08572.X
T. W. Håland, E. Boye, T. Stokke, B. Grallert, R. G. Syljuåsen, Simultaneous measurement of passage through the restriction point and MCM loading in single cells Nucleic Acids Research. ,vol. 43, ,(2015) , 10.1093/NAR/GKV744
John J. Tyson, Béla Novák, Models in biology: lessons from modeling regulation of the eukaryotic cell cycle BMC Biology. ,vol. 13, pp. 46- 46 ,(2015) , 10.1186/S12915-015-0158-9
Yuichi J. Machida, Jamie K. Teer, Anindya Dutta, Acute reduction of an origin recognition complex (ORC) subunit in human cells reveals a requirement of ORC for Cdk2 activation. Journal of Biological Chemistry. ,vol. 280, pp. 27624- 27630 ,(2005) , 10.1074/JBC.M502615200
A. Zetterberg, O. Larsson, Kinetic analysis of regulatory events in G1 leading to proliferation or quiescence of Swiss 3T3 cells Proceedings of the National Academy of Sciences of the United States of America. ,vol. 82, pp. 5365- 5369 ,(1985) , 10.1073/PNAS.82.16.5365
Amy Johnson, Jan M Skotheim, Start and the Restriction Point Current Opinion in Cell Biology. ,vol. 25, pp. 717- 723 ,(2013) , 10.1016/J.CEB.2013.07.010
Cara L. Lunn, John C. Chrivia, Joseph J. Baldassare, Activation of Cdk2/Cyclin E complexes is dependent on the origin of replication licensing factor Cdc6 in mammalian cells Cell Cycle. ,vol. 9, pp. 4533- 4541 ,(2010) , 10.4161/CC.9.22.13789
James E. Ferrell, Tony Yu-Chen Tsai, Qiong Yang, Modeling the cell cycle: why do certain circuits oscillate? Cell. ,vol. 144, pp. 874- 885 ,(2011) , 10.1016/J.CELL.2011.03.006