Development of a nomogram to achieve ultrathin donor corneal disks for Descemet-stripping automated endothelial keratoplasty

摘要: Purpose To report the predictability of a nomogram for ultrathin donor lamella creation Descemet-stripping automated endothelial keratoplasty (DSAEK) with an microkeratome. Setting Instituto de Oftalmologia La Arruzafa, Cordoba, Spain. Design Prospective nonrandomized consecutive case series. Methods This study enrolled eyes patients in which DSAEK was performed to treat Fuchs dystrophy or bullous keratopathy. Patients macular pathology other vision-limiting were included. The same surgeon all surgeries using keratome (Amadeus II) linked artificial anterior chamber. target thickness from 70 120 μm based on that incorporates advancement speed, blade holder size, and corneal thickness. decimal corrected distance visual acuity (CDVA) at 3 months postoperatively, graft 1 month, complications recorded. Results Fifty-one (60 eyes) enrolled. One month mean 99.33 μm ± 16.97 (SD) (range 67 130 μm). range achieved 96.66% cases (58 eyes). In 32 potential 20/20, postoperative CDVA 0.80 ± 0.16 0.55 1.20). There no during flap preparation, intraoperatively, postoperatively events caused tissue be discarded. Conclusions use microkeratome provided good outcomes thin (≤120 μm). similar those reported Descemet membrane keratoplasty. Financial Disclosure Neither author has financial proprietary interest any material method mentioned.