Signal Intensities in Preoperative MRI Do Not Reflect Proliferative Activity in Meningioma.

摘要: BACKGROUND: Identification of high-grade meningiomas in preoperative magnetic resonance imaging (MRI) is important for optimized surgical strategy and best possible resection. Numerous studies investigated subjectively determined morphological features as predictors tumor biology meningiomas. The aim this study was to identify the predictive value more reliable, quantitatively measured signal intensities MRI differentiation high- low-grade identification with high proliferation rates, respectively. PATIENTS AND METHODS: Sixty-six patients (56 World Health Organization [WHO] grade I, 9 WHO II, 1 I) were included study. Preoperative (fluid-attenuated inversion recovery [FLAIR], T1 precontrast, postcontrast genuine normalized values) correlated Ki-67 expression tissue sections resected Differences between groups (analysis variance) Spearman rho correlation computed using SPSS 22. RESULTS: Mean values FLAIR, native, 323.9 ± 59, 332.8 67.9, 768.5 165.3. (to contralateral white matter) 1.5 0.3, 0.8 0.1, 1.9 0.4. There no significant or expression. Signal did not differ significantly I II/III increased compared (P < 0.01). Objectively (FLAIR, enhancement) distinguish Furthermore, there association representing proliferative activity.