Synthesis and characterization of polyethylene glycols conjugated to polybutylcyanoacrylate nanoparticles
作者： Faezeh Babaei , Seyed Ebrahim Alavi , Hasan Ebrahimi Shahmabadi , Azim Akbarzadeh
DOI: 10.1080/00914037.2016.1263953
关键词: Nuclear chemistry 、 Bromide 、 Nanoparticle 、 Dynamic light scattering 、 Emulsion polymerization 、 Polyethylene glycol 、 Polyethylene 、 Materials science 、 Polymer chemistry 、 Conjugated system 、 Cytotoxicity
摘要: This study aimed to evaluate the cytotoxicity effects of various polyethylene glycols (PEGs), and construction characterization polybutylcyanoacrylate (PBCA) nanoparticles. Cytotoxicity was determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay on rat glioma C6 cell line, PBCA nanoparticles were prepared emulsion polymerization method. Also, characterized dynamic light scattering scanning electron microscopy. The findings showed that PEGs approximately safe inversely proportional with their molecular weights. In addition, size increased reducing weights PEGs. negligible stabilizing functionality demonstrated in this study.
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