作者: Larry G. Arlian
DOI: 10.1146/ANNUREV.ENTO.47.091201.145224
关键词: Immunology 、 Allergy 、 Acari 、 Population 、 Allergic response 、 Arthropod 、 Cockroach 、 Biology 、 Immunotherapy 、 Botany 、 Allergen
摘要: Many species of arthropods are the sources potent allergens that sensitize and induce IgE-mediated allergic reactions in humans. Most these arthropod proteins, response mechanism to is same as it for from other such plant pollens, molds, foods. Aside ingestion crustaceans (shrimp, lobster), among arthropods, humans have greatest contact with insects mites, a result allergies two groups been most frequently reported. Because large number people affected by stinging insects, cockroaches, dust many organisms extensively studied, purified, immunobiochemically characterized some recombinant allergens, produced. Cocktails potential use diagnosis immunotherapy. In this chapter, we review mites reactions. Where information exists, immunobiochemical characterization frequency sensitivity or clinical reactivity human population also reviewed. As background, beginning includes sections define explain reaction mechanism, describe methods naming allergens.