Direct and immune mediated antibody targeting of ERBB receptors in a colorectal cancer cell-line panel

作者: S. Q. Ashraf , A. M. Nicholls , J. L. Wilding , T. G. Ntouroupi , N. J. Mortensen

DOI: 10.1073/PNAS.1218750110

关键词: Tyrosine-kinase inhibitorCancer researchAntibodyLapatinibPertuzumabMonoclonal antibodyTrastuzumabBiologyCetuximabMolecular biologyKRAS

摘要: … PRKAA2 that were all overexpressed in the resistant cell lines. In particular, DOCK4 and PRKAA2 … PRKAA2 encodes a 5-AMP activated kinase that has been implicated as a sensor of …

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