Varied influence of microcystin structural difference on ELISA cross-reactivity and chlorination efficiency of congener mixtures.
作者： Xuexiang He , Benjamin D. Stanford , Craig Adams , Erik J. Rosenfeldt , Eric C. Wert
DOI: 10.1016/J.WATRES.2017.09.037
关键词: Kinetics 、 Reactivity (chemistry) 、 Microcystin 、 Cross-reactivity 、 Chlorine 、 Congener 、 Liquid chromatography–mass spectrometry 、 Chemistry 、 Cyanobacteria 、 Chromatography
摘要: Abstract Enzyme-linked immunosorbent assay (ELISA) is an antibody-based analytical method that has been widely applied in water treatment utilities for the screening of toxic cyanobacteria metabolites such as microcystins (MCs). However, it unknown how minor structural difference MCs may impact their chlorination kinetics and measurement via ELISA method. It was found this study that, regardless experimental conditions (n = 21), there no MC-YR or MC-LY residual, while different removal rates other were observed (MC-RR > MC-LR > MC-LA ∼ MC-LF) measured by liquid chromatography tandem mass spectrometry (LC-MS/MS), which consistent with relative reactivity amino acid variables free chlorine. The total generally lower than LC-MS/MS. By incorporating both results, existence ADDA-containing byproducts had a higher sensitivity toward kit demonstrated, after excluding contribution cross-reactivity parent MCs. should be noted, however, cross-reactivities could influenced not only MC congeners, but also mixtures kit.
sci-hub.se 参考文章(33)
Eric C. Wert, Julie A. Korak, Rebecca A. Trenholm, Fernando L. Rosario-Ortiz, Effect of oxidant exposure on the release of intracellular microcystin, MIB, and geosmin from three cyanobacteria species Water Research. ,vol. 52, pp. 251- 259 ,(2014) , 10.1016/J.WATRES.2013.11.001
Lalita N. Sangolkar, Sarika S. Maske, Tapan Chakrabarti, Methods for determining microcystins (peptide hepatotoxins) and microcystin-producing cyanobacteria. Water Research. ,vol. 40, pp. 3485- 3496 ,(2006) , 10.1016/J.WATRES.2006.08.010
Marie Deborde, Urs von Gunten, Reactions of chlorine with inorganic and organic compounds during water treatment—Kinetics and mechanisms: A critical review Water Research. ,vol. 42, pp. 13- 51 ,(2008) , 10.1016/J.WATRES.2007.07.025
Xuexiang He, Armah A. de la Cruz, Anastasia Hiskia, Triantafyllos Kaloudis, Kevin O'Shea, Dionysios D. Dionysiou, Destruction of microcystins (cyanotoxins) by UV-254 nm-based direct photolysis and advanced oxidation processes (AOPs): influence of variable amino acids on the degradation kinetics and reaction mechanisms. Water Research. ,vol. 74, pp. 227- 238 ,(2015) , 10.1016/J.WATRES.2015.02.011
Quiblier Catherine, Wood Susanna, Echenique-Subiabre Isidora, Heath Mark, Villeneuve Aurélie, Humbert Jean-François, A review of current knowledge on toxic benthic freshwater cyanobacteria--ecology, toxin production and risk management. Water Research. ,vol. 47, pp. 5464- 5479 ,(2013) , 10.1016/J.WATRES.2013.06.042
J. Kevin Judice, Jon S. Thorson, Eli Chapman, Elizabeth C. Murphy, Peter G. Schultz, Linear Free Energy Analysis of Hydrogen Bonding in Proteins Journal of the American Chemical Society. ,vol. 117, pp. 1157- 1158 ,(1995) , 10.1021/JA00108A044
Jiehao Guan, Yi-Cheng Wang, Sundaram Gunasekaran, Using L-arginine-functionalized gold nanorods for visible detection of mercury(II) ions. Journal of Food Science. ,vol. 80, ,(2015) , 10.1111/1750-3841.12811
Armah A. de la Cruz, Anastasia Hiskia, Triantafyllos Kaloudis, Neil Chernoff, Donna Hill, Maria G. Antoniou, Xuexiang He, Keith Loftin, Kevin O'Shea, Cen Zhao, Miguel Pelaez, Changseok Han, Trevor J. Lynch, Dionysios D. Dionysiou, A review on cylindrospermopsin: the global occurrence, detection, toxicity and degradation of a potent cyanotoxin Environmental Science: Processes & Impacts. ,vol. 15, pp. 1979- 2003 ,(2013) , 10.1039/C3EM00353A
Juan L. Acero, Eva Rodriguez, Jussi Meriluoto, Kinetics of reactions between chlorine and the cyanobacterial toxins microcystins Water Research. ,vol. 39, pp. 1628- 1638 ,(2005) , 10.1016/J.WATRES.2005.01.022
J. William Schopf, Fossil evidence of Archaean life Philosophical Transactions of the Royal Society B. ,vol. 361, pp. 869- 885 ,(2006) , 10.1098/RSTB.2006.1834