A reappraisal of human β MSH
作者： GLENYS A. BLOOMFIELD , A. P. SCOTT , P. J. LOWRY , J. J. H. GILKES , LESLEY H. REES
DOI: 10.1038/252492A0
关键词: Enzyme 、 Pituitary gland 、 Amino acid 、 Biological activity 、 Peptide sequence 、 Endocrinology 、 Radioimmunoassay 、 Chemistry 、 Melanocyte-stimulating hormone 、 Peptide 、 Internal medicine 、 Molecular biology
摘要: A PEPTIDE containing 22 amino acids has been isolated from human pituitaries and, because of its structural resemblance to the octapeptide hormones previously pig, ox and sheep similar pigment-dispersing biological activity in lower vertebrates, called β-melanocyte stimulating hormone (β MSH)1. The discovery analysis two related pituitary peptides2,3 β- γ-lipotrophin LPH γ LPH)1 which showed that comprised first 1–58 β MSH origin, 41–58 sequence both these molecules (Table 1), led Chretien Li suggest was formed by enzymatic cleavage LPH, representing intermediate compound.
harvard.edu
nature.com
sci-hub.se 参考文章(11)
Alexander P. Scott, Philip J. Lowry, Adrenocorticotrophic and melanocyte-stimulating peptides in the human pituitary Biochemical Journal. ,vol. 139, pp. 593- 602 ,(1974) , 10.1042/BJ1390593
KAORU ABE, DONALD P. ISLAND, GRANT W. LIDDLE, NORMAN FLEISCHER, WENDELL E. NICHOLSON, Radioimmunologic evidence for alpha-MSH (melanocyte stimulating hormone) in human pituitary and tumor tissues. The Journal of Clinical Endocrinology and Metabolism. ,vol. 27, pp. 46- 52 ,(1967) , 10.1210/JCEM-27-1-46
J. G. RATCLIFFE, A. P. SCOTT, H. P. J. BENNETT, P. J. LOWRY, C. McMARTIN, J. A. STRONG, P. R. WALBAUM, Production of a corticotrophin-like intermediate lobe peptide and of corticotrophin by a bronchial carcinoid tumour. Clinical Endocrinology. ,vol. 2, pp. 51- 55 ,(1973) , 10.1111/J.1365-2265.1973.TB03484.X
Kaoru Abe, Wendell E. Nicholson, Grant W. Liddle, David N. Orth, Donald P. Island, Normal and abnormal regulation of β-MSH in man Journal of Clinical Investigation. ,vol. 48, pp. 1580- 1585 ,(1969) , 10.1172/JCI106123
H.B.F. Dixon, Chromatographic isolations of pig and human melanocyte-stimulating hormones Biochimica et Biophysica Acta. ,vol. 37, pp. 38- 42 ,(1960) , 10.1016/0006-3002(60)90075-5
CHOH HAO LI, LIVIO BARNAFI, MICHEL CHRÉTIEN, DAVID CHUNG, Isolation and Amino-acid Sequence of β-LPH from Sheep Pituitary Glands Nature. ,vol. 208, pp. 1093- 1094 ,(1965) , 10.1038/2081093B0
MENACHEM SHAPIRO, WENDELL E. NICHOLSON, DAVID N. ORTH, WILLIAM M. MITCHELL, GRANT W. LIDDLE, Differences Between Ectopic MSH and Pituitary MSH The Journal of Clinical Endocrinology and Metabolism. ,vol. 33, pp. 377- 381 ,(1971) , 10.1210/JCEM-33-3-377
ROSALYN S. YALOW, SOLOMON A. BERSON, Characteristics of "big ACTH" in human plasma and pituitary extracts. The Journal of Clinical Endocrinology and Metabolism. ,vol. 36, pp. 415- 423 ,(1973) , 10.1210/JCEM-36-3-415
M. Chrétien, Choh Hao Li, Erratum: Isolation, purification, and characterization of γ-lipotropic hormone from sheep pituitary glands Biochemistry and Cell Biology. ,vol. 45, pp. 1163- 1174 ,(1967) , 10.1139/O67-133
Albert Segaloff, Methods in investigative and diagnostic endocrinology Steroids. ,vol. 26, pp. 395- ,(1975) , 10.1016/0039-128X(75)90085-9