作者: JONAS COHLER
DOI: 10.1001/ARCHPSYC.1966.01730150055009
关键词: Psychiatry 、 Clinical psychology 、 Double blind 、 Control (linguistics) 、 Blindness 、 Alternative medicine 、 Active control 、 Statement (logic) 、 Psychology
摘要: AT THE onset of their research into double-blind studies the authors took particular note a statement by Committee on Research Group for Advancement Psychiatry. 1 This suggests that inert placebos, as they are frequently employed in studies, fail to reproduce essential symptoms and side effects experienced patients receiving an active drug; judges turn perceive subtle differences between "drug" "control" groups, hence eliminating from design genuine "blindness." Other investigations concerning designs had suggested use control substance which would mimic drug. 2-5 The present investigators have reported attempts develop such two previous findings summarized below. 6,7 In first these using inactive