Risk factors for the recurrence of the congenital diaphragmatic hernia-report from the long-term follow-up study of Japanese CDH study group.

摘要: Aim of the Study Few follow-up studies focused on recurrence regarding postoperative course congenital diaphragmatic hernia (CDH) survivors. The aim this study was to report risk factor for CDH patients who had during follow-up. Materials and Methods A multicenter retrospective survey conducted neonates diagnosed have between January 2006 December 2010. Follow-up September 2013 October (ethical approval: No. 25–222). Nine institutions agreed participate in survey. Out 228, 182 (79.8%) were alive 180 included study. Two excluded because defect not repaired at primary operation. divided into group (n = 21) nonrecurrence (n = 159). Postnatal variables compared these two groups. Baseline which showed significance univariate analysis entered multiple logistic regression analyzing recurrence. A value p  Main Results Out 180, 21 (11.7%) Five (2.8%) before discharge 16 (8.9%) after discharge. Univariate that liver herniation (crude odds ratio [OR], 7.4; 95% confidence interval [CI], 2.73–23.68), size C D, proposed by Study Group OR, 7.09; CI, 2.73–19.99) patch repair 5.00; 1.91–14.70) factors. Multivariate (adjusted 3.96; 1.01–16.92) Conclusion A wide spectrum disease severity rarity mask patients. This only predict herniation. These data will be helpful providing information long-term