Effects of garlic coated tablets in peripheral arterial occlusive disease.

作者: H. Kiesewetter , F. Jung , E.M. Jung , J. Blume , C. Mrowietz

DOI: 10.1007/BF00186628

关键词: Randomized controlled trialCoated tabletsInternal medicineGARLIC POWDERPlacebo groupPeripheral arterial occlusive diseaseCholesterolBlood pressureSurgeryMedicineIntermittent claudicationGastroenterology

摘要: For the first time, a weak clinical efficacy of 12-week therapy with garlic powder (daily dose, 800 mg) is demonstrated in patients peripheral arterial occlusive disease stage II. The increase walking distance verum group by 46 m (from 161.0 ± 65.1 to 207.1 85.0 m) was significantly higher (P<0.05) than placebo (by 31 m, from 172.0 60.9 203.1 72.8). Both groups received physical twice week. diastolic blood pressure, spontaneous thrombocyte aggregation, plasma viscosity, and cholesterol concentration also decreased significantly. Body weight maintained. It quite interesting that garlic-specific did not appear occur until 5th week treatment, connected simultaneous decrease aggregation. Therefore, may be an appropriate agent especially for long-term treatment incipient intermittent claudication.

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