Synthesis of 5-(Sulfamoylmethyl)indoles by Mild Negishi Coupling and Their Application in Almotriptan
作者： Xiaolong Li , Rui Qiu , Weili Wan , Xu Cheng , Yi He
DOI: 10.1007/S40242-015-5030-5
关键词: Chemistry 、 Yield (chemistry) 、 Organic chemistry 、 Negishi coupling 、 Tryptamines 、 Almotriptan
摘要: A new synthetic route of almotriptan was described. The application Negishi coupling reaction simplified the process and significantly improved yield. also expected to be general for synthesis other tryptamines like sumatriptan avitriptan.
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