Histone modification dynamics at H3K27 are associated with altered transcription of in planta induced genes in Magnaporthe oryzae.
作者： David E. Cook , Jun Huang , Wei Zhang
DOI: 10.1371/JOURNAL.PGEN.1009376
关键词: Gene expression 、 Gene 、 Chromatin immunoprecipitation 、 Histone 、 Biology 、 Regulation of gene expression 、 Transcription (biology) 、 Cell biology 、 Gene silencing 、 Effector
摘要: Transcriptional dynamic in response to environmental and developmental cues are fundamental to biology, yet many mechanistic aspects are poorly understood. One such example is fungal plant pathogens, which use secreted proteins and small molecules, termed effectors, to suppress host immunity and promote colonization. Effectors are highly expressed in planta but remain transcriptionally repressed ex planta, but our mechanistic understanding of these transcriptional dynamics remains limited. We tested the hypothesis …
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