Mitotic activity in the subependymal plate of rats and the long-term consequences of X-irradiation

作者: J.B Cavanagh , J.W Hopewell

DOI: 10.1016/0022-510X(72)90172-4

关键词: NecrosisPathologySubependymal zoneHyperintensityPopulationCellular basisWhite matter necrosisBiologyIrradiationMitosis

摘要: Abstract The mitotic activity of the subependymal plate rats following exposure to doses radiation from 200–4000 rads has been studied over 1 year. Good recovery in cell population and numbers occurs month after 200 rad, 3 months 800 6 9 2000 rad. After 4000 rad severe depopulation cells which animals fail recover. Animals die last dose delayed radiation-induced white matter lesions. Certain aspects cellular basis necrosis are discussed it is concluded that inter-related but not interdependent.

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