Mechanisms of aromatase inhibitor resistance
作者： Cynthia X. Ma , Tomás Reinert , Izabela Chmielewska , Matthew J. Ellis
DOI: 10.1038/NRC3920
关键词: Pharmacology 、 Medicine 、 Breast cancer 、 Hormone receptor 、 Aromatase inhibitor 、 Cancer research 、 Oncology
摘要: This Review discusses the mechanisms underlying resistance to aromatase inhibitor (AI) therapy of patients with oestrogen receptor-positive (ER+) breast cancer, and also assesses possible therapeutic options for overcoming AI resistance.
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