IL-10 gene promoter polymorphisms in rheumatoid arthritis

作者: Ali Hajeer , Mark Lazarus , David Turner , Rizgar Mageed , Jiri Vencovsky

DOI: 10.1080/030097498441029

关键词: GenotypeHaplotypePromoterPolymorphism (computer science)Rheumatoid factorGenetic determinismBiologyAlleleImmunologyAllele frequency

摘要: … In RA patients, both serum and synovial £uid IL-10 levels are increased, and produced mainly by non-T cell populations (9). Endogenous IL-10 acts as an anti-in£ammatory cytokine in …

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