Use of contemporary biomaterials in chronic osteomyelitis treatment: clinical lessons learned and literature review

作者: Jan AP Geurts , Tom AG van Vugt , Jacobus JC Arts , None

DOI: 10.1002/JOR.24896

关键词: MedicineBone InfectionChronic osteomyelitisBone regenerationAntimicrobialIntensive care medicineAntibiotic resistance

摘要: Chronic osteomyelitis has always been a therapeutic challenge for patient and surgeon due to the specific problems related with bone infection bacterial biofilm eradication. Other than being cause of or facilitating spread persistence infection, biomaterials are also becoming tool in treatment infection. Certain novel have unique ideal properties that render them perfectly suited combat therefore used more chronic infections. In case treatment, there is still debate whether these should be focused on regeneration and/or their antimicrobial properties. These will even greater importance emerging resistance. This review highlights indications use material some commonly contemporary this indication as well clinical experience literature overview.

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