Age and serum lactate dehydrogenase level are independent prognostic factors in human immunodeficiency virus-related non-Hodgkin's lymphomas: a single-institute study of 96 patients.
作者： E Vaccher , U Tirelli , M Spina , R Talamini , D Errante
DOI: 10.1200/JCO.1996.14.8.2217
关键词: Performance status 、 Pathology 、 Combination chemotherapy 、 Internal medicine 、 Extranodal Involvement 、 Oncology 、 Cohort 、 Population 、 Stage (cooking) 、 Lymphoma 、 Immunopathology 、 Medicine
摘要: PURPOSEThe role of classical pragnostic factors (ie, age, performance status [PS], stage, extranodal involvement, and serum lactate dehydrogenase [LDH] level) included in the International Index for diffuse large-cell non-Hodgkin's lymphoma (NHL) general population is presently unknown setting human immunodeficiency virus (HIV). To assess prognostic value these HIV-related NHL, we reviewed cohort patients with NHL diagnosed treated combination chemotherapy (CT) at our institution.PATIENTS AND METHODSNinety-six systemic CT regimens between September 1987 December 1993 Centro di Riferimento Oncologico, Aviano, Italy, were studied. All clinical laboratory data evaluated by univariate multivariate analyses, using overall survival as end point.RESULTSComplete remission (CR) occurred 48% patients; median disease-free surviv...
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