摘要: In diesem Kapitel werden die wesentlichen humangenetischen Konzepte dargestellt, fur das Verstandnis der Pathogenese von Tumorerkrankungen bei Kindern und Jugendlichen Tumorpradisposition Bedeutung sind. Es wer den diese Thematik wichtigen Strukturen des Genoms sowie unterschiedlichen Arten Konsequenzen mit einer Tumorerkrankung assoziierten Mutationen epigenetischen Storungen erortert klinische Relevanz daraus resultierenden Erkenntnisse aufgezeigt.
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