Dissolution of hydrocortisone in human and simulated intestinal fluids.

作者: Betty Lomstein Pedersen , Helle Brøndsted , Hans Lennernäs , Finn Norring Christensen , Anette Müllertz

DOI: 10.1023/A:1007517414200

关键词: DissolutionIntestinal juiceChromatographyPulmonary surfactantSolubilityBiological fluidPharmacology toxicologyChemistry

摘要: Purpose. To compare solubility and dissolution rate of hydrocortisonein aspirated human intestinal fluids (HIFs) with simulated intestinalfluids (SIFs) buffer.

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