Solubilization of steroid hormones by polyoxyethylene lauryl ether.

摘要: As a further approach to an understanding of relationship between the magnitudes micellar solubilization and hydrophobicities solubilizates, steroid hormones (19 species) were selected explore meaning intercept b value. Two linear free energy relationships established aqueous-polyoxyethylene lauryl ether partition coefficient (K) (Poctanol) aqueous solution n-octanol. One consisted steroids carrying fluorine atom at carbon 9 other those no atom. The value predicted that are solubilized in outer layer mantle while others incorporated into rather inner position, which was consistent with experimental results.