Macrophage Myeloperoxidase Regulation by Granulocyte Macrophage Colony-Stimulating Factor in Human Atherosclerosis and Implications in Acute Coronary Syndromes

作者: Seigo Sugiyama , Yoshikatsu Okada , Galina K. Sukhova , Renu Virmani , Jay W. Heinecke

DOI: 10.1016/S0002-9440(10)64036-9

关键词: ImmunologyCD40Granulocyte macrophage colony-stimulating factorMyeloperoxidaseGranulocyteGranulocyte macrophage colony-stimulating factor receptorInflammationBiologyAtheromaMacrophagePathology and Forensic Medicine

摘要: Inflammation and oxidative stress contribute to the pathogenesis of many human diseases including atherosclerosis. Advanced human atheroma contains high levels of the enzyme …

参考文章(54)
A. J. Tigges, P. K. Das, A. C. van der Wal, A. E. Becker, Macrophage differentiation in atherosclerosis. An in situ immunohistochemical analysis in humans. American Journal of Pathology. ,vol. 141, pp. 161- 168 ,(1992)
S. J. Klebanoff, M. G. Kinsella, T. N. Wight, Degradation of endothelial cell matrix heparan sulfate proteoglycan by elastase and the myeloperoxidase-H2O2-chloride system. American Journal of Pathology. ,vol. 143, pp. 907- 917 ,(1993)
Anthony J. Kettle, Christine C. Winterbourn, [53] Assays for the chlorination activity of myeloperoxidase Methods in Enzymology. ,vol. 233, pp. 502- 512 ,(1994) , 10.1016/S0076-6879(94)33056-5
John I. Gallin, Ralph Snyderman, Ira M. Goldstein, Inflammation: Basic principles and clinical correlates ,(1988)
Ernst Malle, Georg Waeg, Renate Schreiber, Elisabeth F. Gröne, Wolfgang Sattler, Hermann-Josef Gröne, Immunohistochemical evidence for the myeloperoxidase/H2O2/halide system in human atherosclerotic lesions. Colocalization of myeloperoxidase and hypochlorite-modified proteins FEBS Journal. ,vol. 267, pp. 4495- 4503 ,(2000) , 10.1046/J.1432-1327.2000.01498.X
Dianne M. Mueller, Jay W. Heinecke, Marina I. Savenkova, Tyrosyl radical generated by myeloperoxidase is a physiological catalyst for the initiation of lipid peroxidation in low density lipoprotein Journal of Biological Chemistry. ,vol. 269, pp. 20394- 20400 ,(1994) , 10.1016/S0021-9258(17)32005-7
Jay W. Heinecke, MECHANISMS OF OXIDATIVE DAMAGE OF LOW DENSITY LIPOPROTEIN IN HUMAN ATHEROSCLEROSIS Current Opinion in Lipidology. ,vol. 8, pp. 268- 274 ,(1997) , 10.1097/00041433-199710000-00005
J W Heinecke, W Li, G A Francis, J A Goldstein, Tyrosyl radical generated by myeloperoxidase catalyzes the oxidative cross-linking of proteins Journal of Clinical Investigation. ,vol. 91, pp. 2866- 2872 ,(1993) , 10.1172/JCI116531
Christiaan Leeuwenburgh, Jane E. Rasmussen, Fong Fu Hsu, Dianne M. Mueller, Subramaniam Pennathur, Jay W. Heinecke, Mass Spectrometric Quantification of Markers for Protein Oxidation by Tyrosyl Radical, Copper, and Hydroxyl Radical in Low Density Lipoprotein Isolated from Human Atherosclerotic Plaques * Journal of Biological Chemistry. ,vol. 272, pp. 3520- 3526 ,(1997) , 10.1074/JBC.272.6.3520
Cesar Labarca, Kenneth Paigen, A simple, rapid, and sensitive DNA assay procedure. Analytical Biochemistry. ,vol. 102, pp. 344- 352 ,(1980) , 10.1016/0003-2697(80)90165-7