Residual Risk and Biology of the Disease: Implications for Plaque Imaging

摘要: Atherosclerotic disease is highly prevalent in Western countries and associated with morbidity, mortality, a significant economic burden. Even established anti-atherosclerotic medical therapies, many patients continue to experience clinical events. This residual risk highlights the importance of stratification strategies additional therapies achieve more reductions cardiovascular risk. Numerous lines evidence suggest that atherogenic lipids including HDL cholesterol, triglycerides, non-HDL cholesterol contribute progression atherosclerosis Moreover, emerging biomarkers enable us predict future Noninvasive invasive anatomical imaging modalities also have great capabilities refine assessment. Furthermore, molecular techniques are developing directly visualize inflammation, apoptosis, thrombotic angiogenesis activity within mature atherosclerotic plaques. The measurement atheroma burden potential evaluate risks existing each individual. future, combination various plaque may accurate identification high-risk having who need intensive interventions.