Late hemorrhagic cystitis following low-dose cyclophosphamide therapy

作者: Fray F. Marshall , Harry F. Klinefelter

DOI: 10.1016/0090-4295(79)90526-0

关键词: Malignant diseaseDrugRheumatoid arthritisLow dose cyclophosphamideCyclophosphamide therapyInternal medicineImmunologyHemorrhagic cystitisLow dosageMedicineCyclophosphamideGastroenterology

摘要: Hemorrhagic cystitis is a recognized acute complication of cyclophosphamide (Cytoxan) therapy in the treatment malignant disease. More recently, lower dose, long-term has been used autoimmune diseases including rheumatoid arthritis. In 3 patients hemorrhagic developed after for Even low dosage, this drug may cause cystitis.

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