Syphilis treatment: old and new

摘要: Syphilis has challenged scientists and clinicians since its first appearance in the late 1400s debate continues to surround best practice management. Difficulties defining goals of successful treatment have contributed problems determining recommendations for ideal Treatment regimens currently use were developed before randomised controlled trials became standard. This, combined with national differences disease definition, staging varying interpretations studies, as well emergence complicating comorbid conditions, such HIV, resulted a lack consensus treatment. This paper will discuss history current syphilis focusing on dilemmas faced by today, including resistant strain. Despite difference between guidelines, penicillin G largely remains choice. Close follow up, monitoring ensuring adequate compliance remain most important as...