Loss of BRCA1 expression leads to worse survival in patients with gastric carcinoma
作者： Zi-Zhen Zhang , Yuan Jie Charles Liu , Xiao-Lu Yin , Ping Zhan , Yi Gu
关键词: Stomach 、 Brca1 protein 、 Gastric carcinoma 、 Cancer research 、 In patient 、 Homologous Recombination Deficiency 、 Homologous recombination 、 Young adult 、 Biology 、 Adenocarcinoma 、 Gastroenterology 、 General Medicine
摘要: CONCLUSION: Our results support the hypothesis that homologous recombination deficiency plays an important role in progression of gastric carcinoma. Loss expression BRCA1 and MDC1 may serve as predictive factors tumor development or GC patients.
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