The relevance of the DNA index and proliferation rate in the grading of benign and malignant soft tissue tumors

摘要: The relevance of the DNA index (DI) to malignancy grading and relationships between mitotic score, Ki-67 proportion cells in G1-phase (G1PF) cell cycle, as proliferative indicators, were investigated benign (n = 8) malignant 46) soft tissue sarcomas. Although DI was not found be related histology sarcomas, it associated with grade, i.e., 14%, 25%, 42%, 86% benign, Grade 1, 2, 3, respectively had a greater than 1. aneuploidy tumors is discussed literature reviewed. A subgroup 13) both low score value. However, distinct correlation could shown. For tumours G1PF DI, occurred diploid content. Low scores observed 59% 20% aneuploid tumors. appeared that correlated. In conclusion, (1) 1 predominantly high values, (2) most 3 (86%) (3) group 2 divided into two subgroups either characteristics displayed by (DI scores, G1PF) or exhibited G1PF). Hence, supplementary tumors, G1PF, useful prognostic parameters