Nutrition in HIV-Infected Infants and Children: Current Knowledge, Existing Challenges, and New Dietary Management Opportunities.
作者：
关键词: Dysbiosis 、 Intensive care medicine 、 Malnutrition 、 Micronutrient 、 Public health 、 Medical nutrition therapy 、 Dietary management 、 Severe Acute Malnutrition 、 Disease burden 、 Medicine
摘要: HIV infection and undernutrition remain significant public health concerns for infants children. In children under these conditions, is one of the leading causes death. Proper management nutrition related complications in groups with increased needs are prominent challenges, particularly HIV-prevalent poor-resource environments. Several studies support complexity relation between infection, nutrition, immune system. These elements interact create a vicious circle poor outcomes. Recent on use probiotics as novel approach to manage microbiome imbalance gut-mucosal impairment gaining attention. This new strategy could help dysbiosis by reducing activation, thereby potentially forestalling unwanted outcomes HIV. However, existing trials HIV-infected still insufficient. There also conflicting reports dosage effectiveness single or multiple micronutrient supplementation survival severe acute malnutrition. The WHO has published guidelines that include time initiation antiretroviral therapy HIV-pregnant mothers their HIV-exposed children, supplementation, dietary formulations, prevention, therapy. such need be reviewed owing recent advances field nutrition. intervention studies, practical strategies, evidence-based reduce disease burden, improve adherence treatment regimen, enhance health, well-being review provides up-to-date scientific information current knowledge challenges Moreover, it presents research findings incorporated into guidelines.
sci-hub.st 参考文章(108)
Marwa K. Ibrahim, Mara Zambruni, Christopher L. Melby, Peter C. Melby, Impact of Childhood Malnutrition on Host Defense and Infection Clinical Microbiology Reviews. ,vol. 30, pp. 919- 971 ,(2017) , 10.1128/CMR.00119-16
R C Carter, R Kupka, K Manji, C M McDonald, S Aboud, J G Erhardt, K Gosselin, R Kisenge, E Liu, W Fawzi, C P Duggan, Zinc and multivitamin supplementation have contrasting effects on infant iron status: a randomized, double-blind, placebo-controlled clinical trial European Journal of Clinical Nutrition. ,vol. 72, pp. 130- 135 ,(2018) , 10.1038/EJCN.2017.138
Allison Ross Eckard, Mary Ann OʼRiordan, Julia C. Rosebush, Joshua H. Ruff, Ann Chahroudi, Danielle Labbato, Julie E. Daniels, Monika Uribe-Leitz, Vin Tangpricha, Grace A. McComsey, Effects of Vitamin D Supplementation on Bone Mineral Density and Bone Markers in HIV-Infected Youth JAIDS Journal of Acquired Immune Deficiency Syndromes. ,vol. 76, pp. 539- 546 ,(2017) , 10.1097/QAI.0000000000001545
Allison Ross Eckard, Mary Ann O’Riordan, Julia C Rosebush, Seungeun Thera Lee, Jakob G Habib, Joshua H Ruff, Danielle Labbato, Julie E Daniels, Monika Uribe-Leitz, Vin Tangpricha, Ann Chahroudi, Grace A McComsey, Vitamin D supplementation decreases immune activation and exhaustion in HIV-1-infected youth. Antiviral Therapy. ,vol. 23, pp. 315- 324 ,(2017) , 10.3851/IMP3199
Julie Jesson, Désiré L Dahourou, Madeleine Amorissani Folquet, Karen Malateste, Caroline Yonaba, Marie-Sylvie N’Gbeche, Sylvie Ouédraogo, Véronique Mea-Assande, Clarisse Amani-Bossé, Stéphane Blanche, Marguerite Timité-Konan, Valériane Leroy, MONOD ANRS 12206 Study Group, Malnutrition, Growth Response and Metabolic Changes Within the First 24 Months After ART Initiation in HIV-infected Children Treated Before the Age of 2 Years in West Africa Pediatric Infectious Disease Journal. ,vol. 37, pp. 781- 787 ,(2018) , 10.1097/INF.0000000000001932
R H Saragih, A I Mardia, G C F Purba, H Syahrini, Association of serum ferritin levels with immunological status and clinical staging of HIV patients: a retrospective study IOP Conference Series: Earth and Environmental Science. ,vol. 125, pp. 012028- ,(2018) , 10.1088/1755-1315/125/1/012028
Fang He, Chenlu Wu, Pan Li, Nengzhang Li, Dong Zhang, Quoqiang Zhu, Wenkai Ren, Yuanyi Peng, Functions and Signaling Pathways of Amino Acids in Intestinal Inflammation BioMed Research International. ,vol. 2018, pp. 9171905- 9171905 ,(2018) , 10.1155/2018/9171905
Jane Mallewa, Alexander J Szubert, Peter Mugyenyi, Ennie Chidziva, Margaret J Thomason, Priscilla Chepkorir, George Abongomera, Keith Baleeta, Anthony Etyang, Colin Warambwa, Betty Melly, Shepherd Mudzingwa, Christine Kelly, Clara Agutu, Helen Wilkes, Sanele Nkomani, Victor Musiime, Abbas Lugemwa, Sarah L Pett, Mutsa Bwakura-Dangarembizi, Andrew J Prendergast, Diana M Gibb, A Sarah Walker, James A Berkley, Cissy Kityo, Priscilla Wavamunno, Esther Nambi, Paul Ocitti, Milly Ndigendawani, Sheila Kabahenda, Mable Kemigisa, Juliet Acen, David Francis Olebo, Gordon Mpamize, Alex Amone, David Okweny, Andrew Mbonye, Florence Nambaziira, Angela Rweyora, Mary Kangah, Beatrice Kabaswahili, James Abach, Joseph Omongin, Irene Aciro, Aleti Philliam, Beatrice Arach, Emmanuel Ocung, Geoffrey Amone, Peter Miles, Claudia Adong, Constance Tumsuiime, Patrick Kidega, Ben Otto, Florence Apio, Andrew Mukuye, Mary Abwola, Fred Ssennono, David Baliruno, Stephen Tuhirwe, Ronald Namisi, Fredrick Kigongo, Dickson Kikyonkyo, Furaha Mushahara, Julian Tusiime, Alex Musiime, Agnes Nankya, Dickens Atwongyeire, Sowal Sirikye, Sula Myalo, Nelson Noowe, Mariam Kasozi, Sandra Mwebe, Lorna Atwine, Tapson Senkindu, Ian Natuhurira, Chrispus Katemba, Emily Ninsiima, Moses Acaku, Joy Kyomuhangi, Rogers Ankunda, Deogratious Tukwasibwe, Lillian Ayesiga, James Hakim, Kusum Nathoo, Andrew Reid, Tawand Mhute, Gloria Tinago, Joyline Bhiri, Misheck Phiri, John Steamer, Ruth Nhema, Godfrey Musoro, Shirley Mutsai, Beauty Nemasango, Columbus Moyo, Stuart Chitongo, Kennias Rashirai, Sydney Vhembo, Brian Mlambo, Buxton Ndemera, Marko Willard, Chipo Berejena, Yeukai Musodza, Patience Matiza, Boniface Mudenge, Vongai Guti, Jay Berkley, Kathryn Maitland, Patricia Njuguna, Shalton Mwaringa, Timothy Etyang, Ken Awuondo, Stephen Wale, Jimmy Shangala, Jefwa Kithunga, Salim Mwarumba, Salma Said Maitha, Robert Mutai, Margaret Lozi Lewa, Gabriel Mwambingu, Alfred Mwanzu, Connie Kalama, Helen Latham, Joyce Shikuku, Amos Fondo, Anne Njogu, Connie Khadenge, Bryan Mwakisha, Abraham Siika, Kara Wools-Kaloustian, Winston Nyandiko, Priscilla Chepkorir-Cheruiyot, Allan Sudoi, Simon Wachira, Betty Meli, Mercy Karoney, Agnes Nzioka, Michael Tanui, Martha Mokaya, Wilson Ekiru, Chris Mboya, Dorothy Mwimali, Cecilia Mengich, Julie Choge, Wilfred Injera, Kennedy Njenga, Salinah Cherutich, Millicent Anyango Orido, Gerald Omondi Lwande, Peter Rutto, None, Effect of ready-to-use supplementary food on mortality in severely immunocompromised HIV-infected individuals in Africa initiating antiretroviral therapy (REALITY): an open-label, parallel-group, randomised controlled trial The Lancet HIV. ,vol. 5, pp. e231- e240 ,(2018) , 10.1016/S2352-3018(18)30038-9
Calixte Ida Penda, Else Carole Eboumbou Moukoko, Nicolas Policarpe Nolla, Olivia Nadia Evindi Abomo, Paul Koki Ndombo, Malnutrition among HIV infected children under 5 years of age at the Laquintinie hospital Douala, Cameroon. The Pan African medical journal. ,vol. 30, pp. 91- 91 ,(2018) , 10.11604/PAMJ.2018.30.91.15832
Erica L Johnson, Sahithi Boggavarapu, Elan S Johnson, Asim A Lal, Parth Agrawal, Siddhartha Kumar Bhaumik, Kaja Murali-Krishna, Rana Chakraborty, Human Cytomegalovirus Enhances Placental Susceptibility and Replication of Human Immunodeficiency Virus Type 1 (HIV-1), Which May Facilitate In Utero HIV-1 Transmission. The Journal of Infectious Diseases. ,vol. 218, pp. 1464- 1473 ,(2018) , 10.1093/INFDIS/JIY327