Increased risk of cancer at multiple sites after gastric surgery for peptic ulcer.

摘要: Of 5018 patients who had undergone gastric surgery at St James Hospital, Balham, least 25 years ago, death certificates have been received for 2768, whilst 1746 are still alive and flagged (Office of Populations, Censuses Surveys (OPCS) will notify us their its cause) only 504 could not be traced. Mortality from cancers various organs has determined using a 'years risk' calculation in five year bands. There was no increase mortality risk any during the first 15 postoperative years, but 20 after operation there significant excess cancer stomach (4.5-fold), also large bowel (1.6-fold), bronchus (3.9-fold), pancreas (4.0-fold), biliary tract (9.1-fold), oesophagus (2.3-fold), bladder (2.4-fold), breast all sites (3.3-fold). These findings consistent with production operated-upon circulating carcinogens latency period.