Regulation of vascular endothelial growth factor-dependent retinal neovascularization by insulin-like growth factor-1 receptor

作者: Lois E. H. Smith , Wei Shen , Carole Perruzzi , Shay Soker , Fumi Kinose

DOI: 10.1038/70963

关键词: Internal medicineVascular endothelial growth factor AEndocrinologyInsulin-like growth factorVascular endothelial growth factor BInsulin-like growth factor 1 receptorVascular endothelial growth factorVascular endothelial growth factor CGrowth factor receptor inhibitorNeovascularizationMedicineGeneral Biochemistry, Genetics and Molecular BiologyGeneral Medicine

摘要: Although insulin-like growth factor 1 (IGF-1) has been associated with retinopathy, proof of a direct relationship has been lacking. Here we show that an IGF-1 receptor antagonist …

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