Mechanisms of Cardiac Hypertrophy and the Development of Heart Failure
作者： Patrice Delafontaine , Marijke Brink , Yao-Hua Song
DOI: 10.1007/978-1-59259-795-6_17
关键词:
摘要: The RAS and the IGF-I system interact at multiple levels to regulate physiological pathological cardiac growth responses. IGF-I promotes survival of skeletal muscle which is salutary in heart failure. AngII down regulates circulating IGF binding proteins, leading increased myocardial apoptosis proteolysis. Preliminary studies reveal significant alterations failure. An imbalance between contributes progression from compensated decompensated failure.
springer.com
sci-hub.st 参考文章(198)
Dan A. Liebermann, Maryla Krajewska, Stanislaw Krajewski, Hong Gang Wang, Barbara Hoffman, John C. Reed, H. K. Lin, Toshiyuki Miyashita, Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo Oncogene. ,vol. 9, pp. 1799- 1805 ,(1994)
P K Lund, B M Moats-Staats, M A Hynes, J G Simmons, M Jansen, A J D'Ercole, J J Van Wyk, Somatomedin-C/insulin-like growth factor-I and insulin-like growth factor-II mRNAs in rat fetal and adult tissues. Journal of Biological Chemistry. ,vol. 261, pp. 14539- 14544 ,(1986) , 10.1016/S0021-9258(18)66903-0
Shoshana Yakar, Lothar Hennighausen, Derek LeRoith, Ling Zhao, Yiping Wu, Circulating insulin-like growth factor-I levels regulate colon cancer growth and metastasis. Cancer Research. ,vol. 62, pp. 1030- 1035 ,(2002)
Vladimir V. Didenko, Peter J. Hornsby, James R. Tunstead, Biotin-labeled hairpin oligonucleotides: probes to detect double-strand breaks in DNA in apoptotic cells American Journal of Pathology. ,vol. 152, pp. 897- 902 ,(1998)
Lois E. H. Smith, Wei Shen, Carole Perruzzi, Shay Soker, Fumi Kinose, Xianghong Xu, Gregory Robinson, Sam Driver, Joyce Bischoff, Bei Zhang, James M. Schaeffer, Donald R. Senger, Regulation of vascular endothelial growth factor-dependent retinal neovascularization by insulin-like growth factor-1 receptor Nature Medicine. ,vol. 5, pp. 1390- 1395 ,(1999) , 10.1038/70963
Pascal Meier, Andrew Finch, Gerard Evan, Apoptosis in development Nature. ,vol. 407, pp. 796- 801 ,(2000) , 10.1038/35037734
M.F. White, C.R. Kahn, The insulin signaling system. Journal of Biological Chemistry. ,vol. 269, pp. 1- 4 ,(1994) , 10.1016/S0021-9258(17)42297-6
Guadalupe Camarero, Carlos Avendaño, Carmen Fernández-Moreno, Angeles Villar, Julio Contreras, Flora de Pablo, José G. Pichel, Isabel Varela-Nieto, Delayed inner ear maturation and neuronal loss in postnatal Igf-1-deficient mice. The Journal of Neuroscience. ,vol. 21, pp. 7630- 7641 ,(2001) , 10.1523/JNEUROSCI.21-19-07630.2001
Morris F. White, The IRS-signalling system: A network of docking proteins that mediate insulin action Insulin Action. ,vol. 182, pp. 3- 11 ,(1998) , 10.1007/978-1-4615-5647-3_1
Xiao-Ming Yin, Kun Wang, Atan Gross, Yongge Zhao, Sandra Zinkel, Barbara Klocke, Kevin A. Roth, Stanley J. Korsmeyer, Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis Nature. ,vol. 400, pp. 886- 891 ,(1999) , 10.1038/23730