作者: Tamie L. Poepping , Richard N. Rankin , David W. Holdsworth
DOI: 10.1016/J.ULTRASMEDBIO.2010.02.005
关键词: Turbulence 、 Pulsatile flow 、 Ultrasound 、 Materials science 、 Turbulence kinetic energy 、 Stenosis 、 Eccentricity (behavior) 、 Biomedical engineering 、 Radiology 、 Hemodynamics 、 Doppler effect
摘要: Hemodynamics play a significant role in stroke risk, where thrombus formation may be accelerated regions of slow or recirculating flow, high shear and increased turbulence. An vitro investigation was performed with pulsed Doppler ultrasound (DUS) using the complete spectral data to investigate three-dimensional (3-D) distribution advanced parameters that have potential for making more specific vivo diagnosis carotid disease risk. The effect stenosis symmetry DUS visualizing recirculation turbulence were explored. used map pulsatile flow four model geometries representing two different plaque symmetries (eccentricity) severities (mild, severe). Qualitative comparisons made patterns visualized digital particle imaging. Color-encoded maps (mean velocity, spectral-broadening index intensity) clearly distinguished disturbed turbulent flow. Distinctly resulted from stenoses equal severity but eccentricity. Noticeable differences seen both size location zones paths high-velocity jets. Highly elevated levels intensity distal severe stenosis. Results demonstrated importance shape, which is typically not considered standard diagnosis, addition severity.