The Recognition System of Dietary Fatty Acids by the Rat Small Intestinal Cells

作者： Takafumi Shintani , Nobuyuki Takahashi , Tohru Fushiki , Etsuro Sugimoto

关键词: Fatty acid 、 Enterocyte 、 Small intestine 、 Somatostatin 、 Biochemistry 、 Calcium 、 Linoleic acid 、 Oleic acid 、 Biology 、 Endocrinology 、 Internal medicine 、 Peptide hormone 、 Biotechnology 、 Organic chemistry 、 Analytical chemistry 、 Applied Microbiology and Biotechnology 、 Molecular biology 、 General Medicine

摘要: Small intestinal epithelial cells interact with a rather high concentration of fatty acids derived from the diet. These directly or indirectly regulate functions small intestine. We report here that linoleic acid and oleic markedly increased influx 45Ca2+ into cell line (IEC 6). By contrast, octanoic acid, methyl linoleate, linolyl alcohol had no effect on influx. Acidic amino acids, alcohol, inhibited acid-induced 45Ca2+, indicating activation by depended chain length was affected presence carboxyl group. Of gastrointestinal hormones, somatostatin specifically 45Ca2+.