Peptide binding motifs and specificities for HLA-DQ molecules

作者: Andrea Baas , Xiaojiang Gao , G. Chelvanayagam

DOI: 10.1007/S002510050680

关键词: Major histocompatibility complexBiologyHistocompatibility genePeptidePlasma protein bindingHLA-DQGeneticsHLA-DQ AntigenBinding sitePeptide binding

摘要: HLA-DQ molecules have been associated with susceptibility to a number of autoimmune and other diseases, possibly through the peptide repertoire that can be presented by different allelic products. It is thus importance understand which peptides bound Recently, model for has described used derive positional environments By combining known binding motifs, set predictions likely anchor motifs many products variants are made in table referred as roadmap specificities.

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