Hemoglobin, altitude and birth weight: does maternal anemia during pregnancy influence fetal growth?

摘要: OBJECTIVE: To investigate the relationship between maternal hemoglobin concentration, altitude and birth weight. STUDY DESIGN: Birth weights in 235 term pregnancies were investigated for their dependence on concentration after other pregnancy-specific influences fetal weight taken into account. The additional predictive value of was assessed using multiple regression. Using published data, to determined, as effect increasing quantitative correlated with assess whether this could account known decrease altitude. RESULTS: ranged from 2,220 4,850 g (mean, 3,505±443), concentrations 9.3 13.5 g/dL 11.6±0.8). Apart variables, variation at constant independently explained 2.6% variance (r=-.18, P=.003). Term re-duced by 89 each 1.0 increase (P<.01). For every 1,000-m altitude, increased 1.52 decreased 117 g. CONCLUSION: correlates negatively concentration. This is consistent well-known high-altitude exposure during pregnancy, which increases both hematocrit blood viscosity lowers within 13% change that can be attributed associated