Biomedical Applications of Polyhydroxyalkanoates.
作者： Subhasree Ray , Vipin Chandra Kalia
DOI: 10.1007/S12088-017-0651-7
关键词: Nanotechnology 、 Biodegradation 、 Biodegradable implants 、 Biocompatibility 、 Stress conditions 、 Chemistry 、 Tissue engineering 、 Drug carrier 、 Biotechnology 、 Polyhydroxyalkanoates 、 High carbon
摘要: Polyhydroxyalkanoates (PHA) are produced by a large number of microbes under stress conditions such as high carbon (C) availability and limitations nutrients nitrogen, potassium, phosphorus, magnesium, oxygen. Here, store C granules PHAs—energy reservoir. PHAs have properties, which quite similar to those synthetic plastics. The unique make them desirable materials for biomedical applications is their biodegradability, biocompatibility, non-toxicity. been found suitable various medical applications: biocontrol agents, drug carriers, biodegradable implants, tissue engineering, memory enhancers, anticancer agents.
springer.com
sci-hub.se 参考文章(113)
Derya Burcu Hazer, Ebru Kılıçay, Baki Hazer, Poly(3-hydroxyalkanoate)s: Diversification and biomedical applications A state of the art review Materials Science and Engineering: C. ,vol. 32, pp. 637- 647 ,(2012) , 10.1016/J.MSEC.2012.01.021
Wolfgang Babel, Jörg-Uwe Ackermann, Uta Breuer, Physiology, Regulation, and Limits of the Synthesis of Poly(3HB) Advances in Biochemical Engineering \/ Biotechnology. ,vol. 71, pp. 125- 157 ,(2001) , 10.1007/3-540-40021-4_4
Simon F. Williams, David P. Martin, Applications of Polyhydroxyalkanoates (PHA) in Medicine and Pharmacy Biopolymers Online. ,(2002) , 10.1002/3527600035.BPOL4004
B Thomas Bäckström, Jane A Brockelbank, Bernd HA Rehm, Recombinant Escherichia coli produces tailor-made biopolyester granules for applications in fluorescence activated cell sorting: functional display of the mouse interleukin-2 and myelin oligodendrocyte glycoprotein. BMC Biotechnology. ,vol. 7, pp. 3- 3 ,(2007) , 10.1186/1472-6750-7-3
Rinat Nigmatullin, Peter Thomas, Barbara Lukasiewicz, Hima Puthussery, Ipsita Roy, Polyhydroxyalkanoates, a family of natural polymers, and their applications in drug delivery Journal of Chemical Technology & Biotechnology. ,vol. 90, pp. 1209- 1221 ,(2015) , 10.1002/JCTB.4685
Carlo Luca Romanò, Sara Scarponi, Enrico Gallazzi, Delia Romanò, Lorenzo Drago, Antibacterial coating of implants in orthopaedics and trauma: a classification proposal in an evolving panorama Journal of Orthopaedic Surgery and Research. ,vol. 10, pp. 157- 157 ,(2015) , 10.1186/S13018-015-0294-5
Felipe C. Cabello, Heavy use of prophylactic antibiotics in aquaculture: a growing problem for human and animal health and for the environment Environmental Microbiology. ,vol. 8, pp. 1137- 1144 ,(2006) , 10.1111/J.1462-2920.2006.01054.X
Nina Dinjaski, Mar Fernández-Gutiérrez, Shivaram Selvam, Francisco J. Parra-Ruiz, Susan M. Lehman, Julio San Román, Ernesto García, José L. García, Andrés J. García, María Auxiliadora Prieto, PHACOS, a functionalized bacterial polyester with bactericidal activity against methicillin-resistant Staphylococcus aureus. Biomaterials. ,vol. 35, pp. 14- 24 ,(2014) , 10.1016/J.BIOMATERIALS.2013.09.059
Anika C. Jahns, Richard G. Haverkamp, Bernd H. A. Rehm, Multifunctional Inorganic-Binding Beads Self-Assembled Inside Engineered Bacteria Bioconjugate Chemistry. ,vol. 19, pp. 2072- 2080 ,(2008) , 10.1021/BC8001979
Seok Jae Lee, Jong Pil Park, Tae Jung Park, Sang Yup Lee, Seongnam Lee, Jung Ki Park, Selective Immobilization of Fusion Proteins on Poly(hydroxyalkanoate) Microbeads Analytical Chemistry. ,vol. 77, pp. 5755- 5759 ,(2005) , 10.1021/AC0505223