Preventive management of hypoglycemia in very low-birthweight infants following indomethacin therapy for patent ductus arteriosus.

摘要: Background: To evaluate the effects of an increase in glucose infusion rate 2 mg/kg per min from basal on prevention hypoglycemia very low-birthweight (VLBW) infants, following indomethacin therapy for patent ductus arteriosus (PDA). Methods: Forty VLBW infants with PDA were given 0.2 intravenously up to three doses. In 15 40 (supplemented group: between April 1995 and March 1996) was increased increments just before initial administration, compared 25 historical control who received a fixed during first 12 h after dose. We evaluated changes blood levels rates both groups. Results: group 11 (44%) had value below mg/dL 60 (mean 32.7 h). contrast only two out supplemented reached level 72 96 but light-for-dates (defined as birthweight 10th percentile gestational age standard intrauterine growth curve). Blood values significantly higher than those h. However, similar h. Conclusions: This retrospective study shows that min, addition pre-existing stable maintenance intake, might prevent against occurrence unexpected therapy.