Increased Incidence of Lymphoma after Injections of Mice with Cells Differing at Weak Histocompatibility Loci

作者: R. L. Walford

DOI: 10.1126/SCIENCE.152.3718.78

关键词: LeukemiaHistocompatibilityTransplantationLymphomaSerologyCongenicImmunologySpleenBiologyNeoplasm

摘要: Newborns of two congenic strains mice, in which the incidence leukemia is low, differing only at weak H-1 locus, were. injected birth with adult spleen cells parent and strain. A marked increase lymphoma ensued those mice both from other The experiment lends some support to idea that transplantation immunologic mechanisms may play a role genesis lymphomas.