Sleep Homeostasis in Humans and Rats

作者: Alexander A. Borbély , Peter Achermann , Lorenz Trachsel , Irene Tobler

DOI: 10.1007/978-1-4614-7599-6_13

关键词: Sleep periodWakefulnessSleep in non-human animalsAudiologyHomeostasisElectroencephalographyCircadian rhythmMedicineSleep deprivationMorning

摘要: This chapter describes a conceptual and mathematical model that postulates two processes determine sleep propensity in humans. Process S is function of wakefulness. Its level declines exponentially during rises The rate decline was estimated from electroencephalographic (EEG) power density values representing slow-wave activity, which had been recorded for regular period as well recovery after extended rise process obtained by interpolating the activity at beginning end periods (6). C represents circadian independent Circadian highest early morning hours lowest afternoon. In model, represented sine modulates threshold defining time termination.

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