作者: Beixue Gao , Qingfei Kong , Yana Zhang , Chawon Yun , Sharon Y. R. Dent
关键词: Biology 、 Cancer research 、 Histone H3 、 Cellular differentiation 、 T cell 、 NFAT 、 Regulation of gene expression 、 T-cell receptor 、 Immune system 、 Regulatory T cell differentiation
摘要: … We have recently shown that the histone deacetylase Sirt1 is recruited to the promoter of Bclaf1 to suppress Bclaf1 gene transcription by attenuating H3K27 acetylation through binding …