The Histone Acetyltransferase Gcn5 Positively Regulates T Cell Activation.

作者: Beixue Gao , Qingfei Kong , Yana Zhang , Chawon Yun , Sharon Y. R. Dent

DOI: 10.4049/JIMMUNOL.1600312

关键词: BiologyCancer researchHistone H3Cellular differentiationT cellNFATRegulation of gene expressionT-cell receptorImmune systemRegulatory T cell differentiation

摘要: … We have recently shown that the histone deacetylase Sirt1 is recruited to the promoter of Bclaf1 to suppress Bclaf1 gene transcription by attenuating H3K27 acetylation through binding …

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