Use of exercise testing in the evaluation of interventional efficacy: an official ERS statement

摘要: This document reviews 1) the measurement properties of commonly used exercise tests in patients with chronic respiratory diseases and 2) published studies on their utilty and/or evaluation obtained from MEDLINE Cochrane Library searches between 1990 March 2015.Exercise are reliable consistently responsive to rehabilitative pharmacological interventions. Thresholds for clinically important changes performance available several tests. In pulmonary arterial hypertension, 6-min walk test (6MWT), peak oxygen uptake ventilation/carbon dioxide output indices appear be variables most vasodilators. While bronchodilators do not always show relevant effects obstructive disease, high-intensity constant work-rate (endurance) (CWRET) considerably more than incremental 6MWTs. High-intensity CWRETs need standardised reduce interindividual variability. Additional physiological information responsiveness can isotime measurements, particularly inspiratory capacity dyspnoea. Less evidence is endurance shuttle test. Although 6MWT less expensive cardiopulmonary testing, two repetitions needed at baseline. All safe when recommended precautions followed, suggesting that no safer others.