Intravenous immunoglobulin for the treatment of childhood encephalitis

作者: Mildred A Iro , Natalie G Martin , Michael Absoud , Andrew J Pollard

DOI: 10.1002/14651858.CD011367.PUB2

关键词: MedicinePathologyAntibodyNeurological dysfunctionViral therapyInflammationGlasgow Coma ScaleImmune systemEncephalitisParenchyma

摘要: Background Encephalitis is a syndrome of neurological dysfunction due to inflammation the brain parenchyma, caused by an infection or exaggerated host immune response, both. Attenuation through modulation response could improve patient outcomes. Biological agents such as immunoglobulin that have both anti‐inflammatory and immunomodulatory properties may therefore be useful adjunctive therapies for people with encephalitis.

参考文章(78)
M D Kazatchkine, F Rossi, Y Sultan, Anti-idiotypes against autoantibodies and alloantibodies to VIII:C (anti-haemophilic factor) are present in therapeutic polyspecific normal immunoglobulins Clinical and Experimental Immunology. ,vol. 74, pp. 311- 316 ,(1988)
Kenneth L Tyler, Acute viral encephalitis. Handbook of Clinical Neurology. ,vol. 112, pp. 1171- 1181 ,(2013) , 10.1016/B978-0-444-52910-7.00038-6
Rajesh RamachandranNair, Mohemmad Rafeequ, Parameswaran Manoj, Ananthanarayanan Girija, Multimodal treatment of acute disseminated encephalomyelitis in children Journal of pediatric neurology. ,vol. 8, pp. 359- 365 ,(2015) , 10.3233/JPN-2010-0412
Noorbakhsh Samile, Tonekaboni Hassan, ACUTE DISSEMINATED ENCEPHALOMYELITIS IN CHILDREN. A DESCRIPTIVE STUDY IN TEHRAN, IRAN Saudi Medical Journal. ,vol. 28, pp. 396- 399 ,(2007)
Thanyalak Tha-In, Jagadeesh Bayry, Herold J. Metselaar, Srini V. Kaveri, Jaap Kwekkeboom, Modulation of the cellular immune system by intravenous immunoglobulin Trends in Immunology. ,vol. 29, pp. 608- 615 ,(2008) , 10.1016/J.IT.2008.08.004
Barbara A Rath, Max von Kleist, Maria E Castillo, Lenka Kolevic, Patricia Caballero, Giselle Soto-Castellares, Angela M Amedee, James E Robinson, David K Katzenstein, Russell B Van Dyke, Richard A Oberhelman, Antiviral Resistance and Correlates of Virologic Failure in the first Cohort of HIV-Infected Children Gaining Access to Structured Antiretroviral Therapy in Lima, Peru: A Cross-Sectional Analysis BMC Infectious Diseases. ,vol. 13, pp. 1- 12 ,(2013) , 10.1186/1471-2334-13-1
R. A. C. Hughes, M. C. Dalakas, D. R. Cornblath, N. Latov, M. E. Weksler, N. Relkin, Clinical applications of intravenous immunoglobulins in neurology Clinical and Experimental Immunology. ,vol. 158, pp. 34- 42 ,(2009) , 10.1111/J.1365-2249.2009.04025.X
J C van Swieten, P J Koudstaal, M C Visser, H J Schouten, J van Gijn, Interobserver agreement for the assessment of handicap in stroke patients. Stroke. ,vol. 19, pp. 604- 607 ,(1988) , 10.1161/01.STR.19.5.604